Most people say 42 and that's probably right. I think they'd also be just as right if they said, cherry tomatoes.
From my personal perspective -
There is no real meaning to life. This is in no way a negative thing to say. In fact, the quest for a deep meaning to life appears to throw some people into an unnecessary panic - especially around mid life.
I mean this statement in a 'huge picture' way. In a way of asking, 'what does a life amount to.'
When you unpick the legacy of most people's lives, it usually amounts to very little with the exception of what might live on in those people they 'touched' in their life time - and this can be both positive and negative. (This might predominantly be their offspring but will to a lesser extent include others.) There are those that leave a huge legacy - the Einsteins, the Curies, the social reformists - but they are a tiny minority. Few of us will achieve such a legacy. Even our minor positive impacts on the world will in the most part become irrelevant in this ever-changing world after we have gone. For example, the work I and others do now, although a necessary step on the way, will seem like an old viewpoint in no time I am sure - but it kept us occupied while we were around (and meant I wasn't free to mug people).
So if, in my opinion, there is no deep meaning to life, then I see a need to look a bit 'smaller.' And to me that is the key. I guess it's like saying, 'stop taking yourself quite so seriously!'
To those around you, you are what you give. I see what a person 'gives' as some point to their life. People give in so many different ways, making their part of the world that bit more pleasant. Some are nurturing, some create things for other to enjoy, some entertain..... I see positive 'giving' as a significant point to life.
Then there is the carpe diem train of thought - hand in hand with the phrase, 'live every day as if it was your last.' Well I might struggle with that. I think an uncomfortable restlessness comes from trying to pack a life with as many 'experiences' as you can muster. Quiet, simple and small pleasures are enough for me most days and, should I be lucky enough to die suddenly in my sleep, will probably fill my last day. It is great to create unusual memories and have striking experiences too, of course, but I also really believe it's even more fantastic to find contentment in everyday things. Our experiences will die with us after all. So seeing the pleasure very readily under our noses might be another point to life.
I also believe that life is about personal growth. I hate the idea of stagnating. Personal growth will, of course be different for everyone. There's always more to learn - skills, knowledge etc. But for me, increasing self awareness helps a person live a life more and more free from patterns and buttons. Free from the patterns and buttons that mean we continue to react to life situations in a way we have been programmed to in the past - that can in many cases mean a repetition of disastrous relationships, destructive behaviour, irrational reactions, poor interpersonal skills, wariness of others, etc. Self awareness sets you free to confidently explore a greater amount of life - more and more free from all those conditioned responses. This can also result in a greater amount of contentment. I'm in agreement with Jung on this. Good company to be in. It also gives you a lifetime's worth of work and therefore keeps you occupied because there is always more to know.
Another significant idea might be that of perspective. I feel that it is a very human condition to make ourselves unnecessarily distressed over things that really do not matter. This notion is a little out of place here but I think of it as an anti-point - what should life not be about. If you were on your death-bed, how much of what might have pre-occupied you in your time in a bad way would you conclude would have been better to have not bothered with. The ability to transcend pettiness is a pretty beneficial and healthy thing to be able to do. Many things would pale into the realms of pettiness on our death-bed - I'm sure!
I feel we are all floundering around - hopefully, often, just pleasantly. Nice innit!